Methyl 2-(m-methoxyphenyl)acetate
Methyl 3-methoxyphenylacetate
CAS: 18927-05-4
Molecular Formula: C10H12O3
Methyl 2-(m-methoxyphenyl)acetate - Names and Identifiers
Methyl 2-(m-methoxyphenyl)acetate - Physico-chemical Properties
| Molecular Formula | C10H12O3 |
| Molar Mass | 180.2 |
| Density | 1.12 |
| Boling Point | 80 °C |
| Flash Point | 86-88°C/0.5mm |
| Water Solubility | Sparingly soluble in water. |
| Vapor Presure | 0.0176mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.5130-1.5180 |
| MDL | MFCD00017205 |
Methyl 2-(m-methoxyphenyl)acetate - Risk and Safety
| Safety Description | S24/25 - Avoid contact with skin and eyes. |
Methyl 2-(m-methoxyphenyl)acetate - Introduction
Methyl 3-methoxyphenylacetate is also known as Methyl p-methoxyphenylacetate, and its chemical formula is C10H12O3. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless liquid
-Smell: Aromatic smell similar to banana
-Density: 1.075g/cm³
-Boiling point: 199-200 ° C
-Melting Point:-
-Solubility: Soluble in ethanol, ether and chloroform, slightly soluble in water
Use:
- Methyl 3-methoxyphenylacetate is widely used in the field of flavors and food additives to enhance the fragrance of fruits such as bananas, peaches, and strawberries.
-It can also be used as a pharmaceutical intermediate for the synthesis of certain drugs.
-In organic synthesis, it can be used as a substrate or reagent to participate in esterification, transesterification, nucleophilic substitution and other reactions.
Method:
-A common preparation method is obtained by reacting p-toluene with methyl formate under acidic conditions. First, P-toluene is heated with an excess of methyl formate in the presence of an acidic catalyst to obtain 3-methoxyphenylacetic acid. Then, it is reacted with methanol under the condition of acid catalysis to produce the final product Methyl 3-methyphenylacetate.
Safety Information:
- Methyl 3-methoxyphenylacetate should avoid contact with skin and eyes because it may cause irritation to the human body.
-Take precautions when using, including wearing appropriate protective gloves and goggles.
-Keep away from open flame or high temperature during operation to avoid combustible gas.
-Keep away from oxidizing agents and strong acids during storage and handling.
-If inhaled or ingested, seek medical attention immediately.
Nature:
-Appearance: colorless liquid
-Smell: Aromatic smell similar to banana
-Density: 1.075g/cm³
-Boiling point: 199-200 ° C
-Melting Point:-
-Solubility: Soluble in ethanol, ether and chloroform, slightly soluble in water
Use:
- Methyl 3-methoxyphenylacetate is widely used in the field of flavors and food additives to enhance the fragrance of fruits such as bananas, peaches, and strawberries.
-It can also be used as a pharmaceutical intermediate for the synthesis of certain drugs.
-In organic synthesis, it can be used as a substrate or reagent to participate in esterification, transesterification, nucleophilic substitution and other reactions.
Method:
-A common preparation method is obtained by reacting p-toluene with methyl formate under acidic conditions. First, P-toluene is heated with an excess of methyl formate in the presence of an acidic catalyst to obtain 3-methoxyphenylacetic acid. Then, it is reacted with methanol under the condition of acid catalysis to produce the final product Methyl 3-methyphenylacetate.
Safety Information:
- Methyl 3-methoxyphenylacetate should avoid contact with skin and eyes because it may cause irritation to the human body.
-Take precautions when using, including wearing appropriate protective gloves and goggles.
-Keep away from open flame or high temperature during operation to avoid combustible gas.
-Keep away from oxidizing agents and strong acids during storage and handling.
-If inhaled or ingested, seek medical attention immediately.
Last Update：2024-04-09 21:01:54
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